The main frustration I feel is the Catch 22 one of people wanting you to have a track record before they will take you on, yet the only way to get that track record is to be published! It is also highly appropriate to use the phrase Catch 22 too given we're talking about getting books out there...
Back to our fictional worlds though - what role does literature play in it? Who "controls" literature? Could your characters be published writers? What form of writing do they use? Do they have stories as we understand them? Who are the publishers in your setting(s)? Does the government exercise any control over what the public can read?
(I like the thought of there being an underground library for those not wanting to just read what is on a government's approved list!).